Does Serrapeptase Cause Hair Loss?

Serrapeptase is a natural, plant-based enzyme that has gained popularity as a supplement for reducing inflammation and breaking down non-living tissue. Some people have started taking it for treating or preventing hair loss as well. However, its actual effects on hair growth and whether it could potentially cause shedding are still unclear based on current research.
Proponents of serrapeptase argue that it may promote hair growth through a few mechanisms:
- As a proteolytic enzyme, serrapeptase breaks down proteins in the extracellular matrix and blood vessels which could improve microcirculation to hair follicles and support their growth.
- Some small clinical trials found that oral or topical application of serrapeptase led to reports of regrowth or increased hair counts in some patients experiencing hair loss.
However, skeptics point to evidence that serrapeptase may also have negative impacts on hair:
- Side effects like muscle soreness and joint pains could exacerbate discomfort already experienced by those struggling with hair shedding.
- Overstimulation of protein degradation may damage the protective functions of the extracellular matrix and expedite the hair loss process.
- A few studies found higher doses or long-term oral intake was associated with mild to moderate shedding.
Overall, there is currently no substantial scientific proof that serrapeptase significantly promotes hair growth in healthy individuals, nor a definitive consensus that it cannot cause hair loss. Due to risk of side effects, it cannot be recommended as a standalone treatment.
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In conclusion, while some small studies tentatively show serrapeptase may support follicles, its impacts remain inconclusive due to inconsistencies in results and potential adverse reactions. Until more extensive research is available, hair loss patients are advised to consult a medical expert regarding whether risks outweigh claimed benefits when considering serrapeptase or any supplement-based treatment approach. Integrated hair systems offer an immediate alternative without such safety uncertainties.